Heart Health / Cholesterol

The cardioprotective effects of Guggul have long been known in Ayurveda. It helps to stop blood clots from forming due to its ability to counter platelet aggregation – a benefit seen in both healthy subjects and those suffering from coronary heart disease.

Also a powerful anti-inflammatory, Guggul has been studied for its effects on patients with hypercholesterolemia (high cholesterol). It was found that subjects who took 2000mg of Guggul extract daily experienced a decline in levels of C-reactive proteins – an indicator of inflammation that is specifically linked to atherosclerosis and is involved in every stage of plaque build up.

Furthermore, Guggul has been found to reduce levels of LDL (low density lipoprotein) and the dangerous VLDL (very low density lipoprotein), whilst increasing HDL (high density lipoprotein), helping to optimise cholesterol ratio to a healthy level. The active compounds found in Guggul include gugulipid and guggulsterone. The mechanism for gugulipid’s cholesterol lowering action appears to be its ability to increase the liver’s metabolism of LDL cholesterol. Guggulsterone increases the uptake of LDL cholesterol from the blood by the liver.

Finally, the powerful antioxidant properties of Guggul protect the heart and blood vessels from oxidative stress, reducing damage to the cells and protecting against heart disease.

Thyroid Health / Weight Loss

The health of the thyroid is directly linked to a healthy metabolism, which in turn will determine one’s ability to lose weight alongside a healthy diet and moderate exercise regime. Numerous studies have shown Guggul to support optimal thyroid health, helping to stimulate the body’s natural ability to regulate metabolism. A study published in “Science Direct” found that Guggul significantly reduced fat mass and improved the mood when taken in conjunction with regular exercise.

Guggul has also been shown to stimulate iodine uptake by the thyroid. Without iodine, the thyroid is unable to make the hormones T3 and T4 – every cell in the body depends upon these thyroid hormones for the regulation of metabolism. By increasing the uptake of iodine and the activity of thyroid hormones, Guggul can help to speed up metabolism and enhance the overall digestive process.

Furthermore, in relation to weight loss, it prevents the conversion of undigested carbohydrates to fat cells and fights the oxidative stress associated with obesity.

Arthritis

The powerful anti-inflammatory action of Guggul is attributed to the active compound guggulsterone. Studies have found it to be comparable to NSAIDS (non-steroidal anti-inflammatory drugs), and have shown that it can suppress the protein complexes known as NF-kappaB that are involved in inflammatory responses of the body.

This is particularly beneficial to sufferers of rheumatoid and osteoarthritis, with one study showing that just 500mg of Guggul extract daily improved pain, stiffness, mobility and function in osteoarthritis patients. Other research has found that it also reduces the thickness of joint swelling which can lead to less pain and discomfort.

Kidney Health

The anti-inflammatory action of Guggul also works to protect the kidneys from damage by infections or drug overuse by inhibiting inflammatory responses. It suppresses inflammatory molecules such as nitric oxide, IL-6, and TNF-alpha, further protecting the kidneys from damage.

Liver Health

Classed as a hepatoprotective herb, Guggul stimulates bile production in the liver which improves the breakdown of fats, boosts the excretion of cholesterol and helps the liver to do its job of detoxification.